Air France flight AF 2221: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Sun 05:32 Boise (BOI) 09:24 Minneapolis/Saint Paul (MSP) 1
AF 2221 Non-stop Airbus A321 (321) 2:52 Effective 2025-12-21 through 2026-01-04
Codeshare flight, operated by Delta Air Lines.(DL 2808)
Sun 05:40 Boise (BOI) 09:30 Minneapolis/Saint Paul (MSP) 1
AF 2221 Non-stop Airbus A321 (321) 2:50 Effective 2025-11-02 through 2025-11-30
Codeshare flight, operated by Delta Air Lines.(DL 2808)
Sun 05:40 Boise (BOI) 09:30 Minneapolis/Saint Paul (MSP) 1
AF 2221 Non-stop Airbus A320 (320) 2:50 Effective 2025-12-07 through 2025-12-14
Codeshare flight, operated by Delta Air Lines.(DL 2808)
Daily 06:05 Memphis (MEM) 10:05 Boston Logan (BOS) A
AF 2221 Non-stop Embraer EMB 175 (E75) 3:00 Effective 2025-09-08 through 2025-10-24
Codeshare flight, operated by Delta Air Lines.(DL 5862)
Sun 08:45 Los Angeles (LAX) 3 14:07 George Bush, Houston (IAH) A
AF 2221 Non-stop Airbus A319 (319) 3:22 Operates only on 2025-06-08
Codeshare flight, operated by Delta Air Lines.(DL 1143)
Wed,Fri,Sun 08:50 Los Angeles (LAX) 3 14:12 George Bush, Houston (IAH) A
AF 2221 Non-stop Airbus A319 (319) 3:22 Effective 2025-05-07 through 2025-05-23
Codeshare flight, operated by Delta Air Lines.(DL 1143)
Wed,Fri,Sun 08:50 Los Angeles (LAX) 3 14:12 George Bush, Houston (IAH) A
AF 2221 Non-stop Airbus A319 (319) 3:22 Effective 2025-05-28 through 2025-06-06
Codeshare flight, operated by Delta Air Lines.(DL 1143)
Wed,Fri,Sun 08:55 Los Angeles (LAX) 3 14:14 George Bush, Houston (IAH) A
AF 2221 Non-stop Airbus A319 (319) 3:19 Valid until 2025-05-04
Codeshare flight, operated by Delta Air Lines.(DL 1143)
Sun 09:20 Los Angeles (LAX) 3 14:39 George Bush, Houston (IAH) A
AF 2221 Non-stop Airbus A319 (319) 3:19 Operates only on 2025-05-25
Codeshare flight, operated by Delta Air Lines.(DL 1143)
Sun 11:54 Jacksonville (OAJ) 13:31 Atlanta (ATL) S
AF 2221 Non-stop Canadair CRJ 900 (CR9) 1:37 Operates only on 2025-06-29
Codeshare flight, operated by Delta Air Lines.(DL 5365)
Mon,Tue,Thu,Sat 12:35 Jacksonville (OAJ) 14:14 Atlanta (ATL) S
AF 2221 Non-stop Canadair CRJ 700 (CR7) 1:39 Valid until 2025-05-06
Codeshare flight, operated by Delta Air Lines.(DL 5365)
Tue,Thu,Sat 12:40 Jacksonville (OAJ) 14:15 Atlanta (ATL) S
AF 2221 Non-stop Canadair CRJ 700 (CR7) 1:35 Effective 2025-05-08 through 2025-05-31
Codeshare flight, operated by Delta Air Lines.(DL 5365)
Thu 12:40 Jacksonville (OAJ) 14:15 Atlanta (ATL) S
AF 2221 Non-stop Canadair CRJ 700 (CR7) 1:35 Operates only on 2025-06-05
Codeshare flight, operated by Delta Air Lines.(DL 5365)
Sat 14:00 Detroit (DTW) M 15:23 Harrisburg (MDT)
AF 2221 Non-stop Canadair CRJ 900 (CR9) 1:23 Operates only on 2025-06-07
Codeshare flight, operated by Delta Air Lines.(DL 3981)
Tue 14:45 Detroit (DTW) M 16:07 Harrisburg (MDT)
AF 2221 Non-stop Canadair CRJ 900 (CR9) 1:22 Operates only on 2025-06-03
Codeshare flight, operated by Delta Air Lines.(DL 3981)
Mon-Sat 16:11 Detroit (DTW) M 17:18 Denver (DEN)
AF 2221 Non-stop Boeing 737-900 (739) 3:07 Effective 2025-06-09 through 2025-07-05
Codeshare flight, operated by Delta Air Lines.(DL 2431)
Mon-Sat 16:15 Detroit (DTW) M 17:27 Denver (DEN)
AF 2221 Non-stop Airbus A321 (321) 3:12 Effective 2025-07-07 through 2025-09-06
Codeshare flight, operated by Delta Air Lines.(DL 2431)
Mon-Sat 16:15 Detroit (DTW) M 17:37 Denver (DEN)
AF 2221 Non-stop Airbus A321 (321) 3:22 Effective from 2026-01-06
Codeshare flight, operated by Delta Air Lines.(DL 2431)
Mon-Sat 16:20 Detroit (DTW) M 17:34 Denver (DEN)
AF 2221 Non-stop Airbus A320 (320) 3:14 Effective 2025-12-20 through 2026-01-05
Codeshare flight, operated by Delta Air Lines.(DL 2431)
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This flight number is listed as serving the following routes:


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Air France flight AF 2221: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Codeshare Flights:
Air France AF2221
05:32
Boise (BOI)

09:24
Minneapolis/Saint Paul (MSP) 1
Effective 2025-12-21 through 2026-01-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2808)
Duration: 2:52, non-stop
Airbus A321 (321)
Air France AF2221
05:40
Boise (BOI)

09:30
Minneapolis/Saint Paul (MSP) 1
Effective 2025-11-02 through 2025-11-30
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2808)
Duration: 2:50, non-stop
Airbus A321 (321)
Air France AF2221
05:40
Boise (BOI)

09:30
Minneapolis/Saint Paul (MSP) 1
Effective 2025-12-07 through 2025-12-14
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 2808)
Duration: 2:50, non-stop
Airbus A320 (320)
Air France AF2221
06:05
Memphis (MEM)

10:05
Boston Logan (BOS) A
Effective 2025-09-08 through 2025-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5862)
Duration: 3:00, non-stop
Embraer EMB 175 (E75)
Air France AF2221
08:45
Los Angeles (LAX) 3

14:07
George Bush, Houston (IAH) A
Operates only on 2025-06-08
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1143)
Duration: 3:22, non-stop
Airbus A319 (319)
Air France AF2221
08:50
Los Angeles (LAX) 3

14:12
George Bush, Houston (IAH) A
Effective 2025-05-07 through 2025-05-23
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1143)
Duration: 3:22, non-stop
Airbus A319 (319)
Air France AF2221
08:50
Los Angeles (LAX) 3

14:12
George Bush, Houston (IAH) A
Effective 2025-05-28 through 2025-06-06
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1143)
Duration: 3:22, non-stop
Airbus A319 (319)
Air France AF2221
08:55
Los Angeles (LAX) 3

14:14
George Bush, Houston (IAH) A
Valid until 2025-05-04
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1143)
Duration: 3:19, non-stop
Airbus A319 (319)
Air France AF2221
09:20
Los Angeles (LAX) 3

14:39
George Bush, Houston (IAH) A
Operates only on 2025-05-25
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 1143)
Duration: 3:19, non-stop
Airbus A319 (319)
Air France AF2221
11:54
Jacksonville (OAJ)

13:31
Atlanta (ATL) S
Operates only on 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Codeshare flight, operated by Delta Air Lines. (DL 5365)
Duration: 1:37, non-stop
Canadair CRJ 900 (CR9)
Air France AF2221
12:35
Jacksonville (OAJ)

14:14
Atlanta (ATL) S
Valid until 2025-05-06
Mon
Tue
Wed
-
Thu
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 5365)
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)
Air France AF2221
12:40
Jacksonville (OAJ)

14:15
Atlanta (ATL) S
Effective 2025-05-08 through 2025-05-31
Mon
-
Tue
Wed
-
Thu
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 5365)
Duration: 1:35, non-stop
Canadair CRJ 700 (CR7)
Air France AF2221
12:40
Jacksonville (OAJ)

14:15
Atlanta (ATL) S
Operates only on 2025-06-05
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 5365)
Duration: 1:35, non-stop
Canadair CRJ 700 (CR7)
Air France AF2221
14:00
Detroit (DTW) M

15:23
Harrisburg (MDT)
Operates only on 2025-06-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 3981)
Duration: 1:23, non-stop
Canadair CRJ 900 (CR9)
Air France AF2221
14:45
Detroit (DTW) M

16:07
Harrisburg (MDT)
Operates only on 2025-06-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 3981)
Duration: 1:22, non-stop
Canadair CRJ 900 (CR9)
Air France AF2221
16:11
Detroit (DTW) M

17:18
Denver (DEN)
Effective 2025-06-09 through 2025-07-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2431)
Duration: 3:07, non-stop
Boeing 737-900 (739)
Air France AF2221
16:15
Detroit (DTW) M

17:27
Denver (DEN)
Effective 2025-07-07 through 2025-09-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2431)
Duration: 3:12, non-stop
Airbus A321 (321)
Air France AF2221
16:15
Detroit (DTW) M

17:37
Denver (DEN)
Effective from 2026-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2431)
Duration: 3:22, non-stop
Airbus A321 (321)
Air France AF2221
16:20
Detroit (DTW) M

17:34
Denver (DEN)
Effective 2025-12-20 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by Delta Air Lines. (DL 2431)
Duration: 3:14, non-stop
Airbus A320 (320)
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This flight number is listed as serving the following routes:
  • Boise (BOI) - Minneapolis/Saint Paul (MSP)
  • Detroit (DTW) - Denver (DEN)
  • Detroit (DTW) - Harrisburg (MDT)
  • Jacksonville (OAJ) - Atlanta (ATL)
  • Los Angeles (LAX) - George Bush, Houston (IAH)
  • Memphis (MEM) - Boston Logan (BOS)
All Air France flights
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