American Airlines flight AA 4422: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Mon 05:25 Pittsburgh (PIT) 07:16 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:51 Operates only on 2025-05-05
Daily 06:00 Memphis (MEM) 09:15 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:15 Valid until 2025-05-04
Daily 06:00 Memphis (MEM) 09:14 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2025-05-06 through 2025-06-04
Sun 06:00 Memphis (MEM) 09:18 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:18 Effective 2025-07-06 through 2025-08-03
Sun 06:02 Memphis (MEM) 09:18 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:16 Effective 2025-06-08 through 2025-06-29
Daily 06:12 Memphis (MEM) 09:29 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2025-10-06 through 2025-10-25
Daily 06:13 Memphis (MEM) 09:29 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:16 Effective 2025-08-06 through 2025-10-05
Mon-Fri 08:19 Ronald Reagan Washington (DCA) 2 09:54 Pensacola (PNS)
AA 4422 Non-stop Embraer EMB 175 (E75) 2:35 Effective 2025-06-05 through 2025-07-04
Sat 08:39 Ronald Reagan Washington (DCA) 2 10:27 Pensacola (PNS)
AA 4422 Non-stop Embraer EMB 175 (E75) 2:48 Effective 2025-06-07 through 2025-06-28
Daily 09:03 New York LaGuardia (LGA) B 10:53 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:50 Effective from 2026-02-12
Daily 09:08 New York LaGuardia (LGA) B 11:01 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:53 Effective 2025-12-03 through 2025-12-17
Daily 09:15 New York LaGuardia (LGA) B 11:06 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2025-10-26 through 2025-11-01
Daily 09:29 New York LaGuardia (LGA) B 11:15 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2025-11-02 through 2025-12-02
Daily 09:35 New York LaGuardia (LGA) B 11:25 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:50 Effective 2025-12-18 through 2026-01-05
Mon-Fri 10:31 Pensacola (PNS) 13:59 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2025-06-05 through 2025-07-04
Daily 10:45 New York LaGuardia (LGA) B 12:38 Wilmington (ILM)
AA 4422 Non-stop Embraer EMB 175 (E75) 1:53 Effective 2026-01-06 through 2026-02-11
Sat 10:57 Pensacola (PNS) 14:24 Ronald Reagan Washington (DCA) 2
AA 4422 Non-stop Embraer EMB 175 (E75) 2:27 Effective 2025-06-07 through 2025-06-28
Daily 11:31 Wilmington (ILM) 13:19 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:48 Effective 2025-12-03 through 2025-12-17
Daily 11:37 Wilmington (ILM) 13:19 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:42 Effective from 2026-02-12
Daily 11:51 Wilmington (ILM) 13:30 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-10-26 through 2025-11-01
Daily 11:54 Wilmington (ILM) 13:33 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2025-11-02 through 2025-12-02
Daily 11:55 Wilmington (ILM) 13:42 New York LaGuardia (LGA) B
AA 4422 Non-stop Embraer EMB 175 (E75) 1:47 Effective 2025-12-18 through 2026-01-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4422: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4422
05:25
Pittsburgh (PIT)

07:16
New York LaGuardia (LGA) B
Operates only on 2025-05-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:00
Memphis (MEM)

09:15
Ronald Reagan Washington (DCA) 2
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:00
Memphis (MEM)

09:14
Ronald Reagan Washington (DCA) 2
Effective 2025-05-06 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:00
Memphis (MEM)

09:18
Ronald Reagan Washington (DCA) 2
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:18, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:02
Memphis (MEM)

09:18
Ronald Reagan Washington (DCA) 2
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:16, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:12
Memphis (MEM)

09:29
Ronald Reagan Washington (DCA) 2
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
06:13
Memphis (MEM)

09:29
Ronald Reagan Washington (DCA) 2
Effective 2025-08-06 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:16, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
08:19
Ronald Reagan Washington (DCA) 2

09:54
Pensacola (PNS)
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
08:39
Ronald Reagan Washington (DCA) 2

10:27
Pensacola (PNS)
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:48, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
09:03
New York LaGuardia (LGA) B

10:53
Wilmington (ILM)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
09:08
New York LaGuardia (LGA) B

11:01
Wilmington (ILM)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
09:15
New York LaGuardia (LGA) B

11:06
Wilmington (ILM)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:51, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
09:29
New York LaGuardia (LGA) B

11:15
Wilmington (ILM)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
09:35
New York LaGuardia (LGA) B

11:25
Wilmington (ILM)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
10:31
Pensacola (PNS)

13:59
Ronald Reagan Washington (DCA) 2
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:28, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
10:45
New York LaGuardia (LGA) B

12:38
Wilmington (ILM)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
10:57
Pensacola (PNS)

14:24
Ronald Reagan Washington (DCA) 2
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:27, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
11:31
Wilmington (ILM)

13:19
New York LaGuardia (LGA) B
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
11:37
Wilmington (ILM)

13:19
New York LaGuardia (LGA) B
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
11:51
Wilmington (ILM)

13:30
New York LaGuardia (LGA) B
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
11:54
Wilmington (ILM)

13:33
New York LaGuardia (LGA) B
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4422
11:55
Wilmington (ILM)

13:42
New York LaGuardia (LGA) B
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Memphis (MEM) - Ronald Reagan Washington (DCA)
  • New York LaGuardia (LGA) - Wilmington (ILM)
  • Pittsburgh (PIT) - New York LaGuardia (LGA)
  • Ronald Reagan Washington (DCA) - Pensacola (PNS)
All American Airlines flights
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