American Airlines flight AA 5216: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Tue 08:00 Chicago O'Hare (ORD) 3 10:16 Dayton (DAY)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:16 Operates only on 2026-01-06
Daily 09:40 Chicago O'Hare (ORD) 3 11:53 Dayton (DAY)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:13 Effective 2025-12-18 through 2026-01-05
Sun 10:23 Pensacola (PNS) 13:42 Ronald Reagan Washington (DCA) 2
AA 5216 Non-stop Canadair CRJ 900 (CR9) 2:19 Effective 2025-05-11 through 2025-06-01
Mon-Sat 10:32 Pensacola (PNS) 13:51 Ronald Reagan Washington (DCA) 2
AA 5216 Non-stop Canadair CRJ 900 (CR9) 2:19 Effective 2025-05-05 through 2025-06-04
Sat 11:27 Philadelphia (PHL) F 12:40 Nashville (BNA)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 2:13 Valid until 2025-05-03
Daily 13:05 Charlotte (CLT) 13:59 Memphis (MEM)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:54 Effective 2025-07-05 through 2025-08-05
Daily 13:10 Charlotte (CLT) 14:03 Memphis (MEM)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:53 Effective 2025-06-05 through 2025-07-04
Daily 14:29 Memphis (MEM) 17:28 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:59 Effective 2025-07-05 through 2025-08-05
Daily 14:33 Memphis (MEM) 17:25 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:52 Effective 2025-06-05 through 2025-07-04
Daily 15:43 Asheville/Hendersonville (AVL) 17:16 Ronald Reagan Washington (DCA) 2
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:33 Effective 2025-08-06 through 2025-09-02
Daily 15:45 Dayton (DAY) 16:10 Chicago O'Hare (ORD) 3
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:25 Effective 2025-12-18 through 2026-01-05
Daily 16:20 Charlotte (CLT) 17:15 Columbia (CAE)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 0:55 Effective 2025-10-26 through 2025-11-01
Daily 16:20 Charlotte (CLT) 17:16 Columbia (CAE)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 0:56 Effective 2025-11-02 through 2025-12-02
Daily 16:20 Charlotte (CLT) 17:20 Columbia (CAE)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:00 Effective 2026-01-07 through 2026-02-11
Daily 16:20 Charlotte (CLT) 17:21 Columbia (CAE)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:01 Effective from 2026-02-12
Daily 18:25 Columbia (CAE) 19:40 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:15 Effective 2026-01-07 through 2026-02-11
Daily 18:27 Columbia (CAE) 19:40 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:13 Effective from 2026-02-12
Daily 18:29 Columbia (CAE) 19:40 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:11 Effective 2025-11-02 through 2025-12-02
Daily 18:34 Columbia (CAE) 19:40 Charlotte (CLT)
AA 5216 Non-stop Canadair CRJ 900 (CR9) 1:06 Effective 2025-10-26 through 2025-11-01
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5216: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5216
08:00
Chicago O'Hare (ORD) 3

10:16
Dayton (DAY)
Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:16, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
09:40
Chicago O'Hare (ORD) 3

11:53
Dayton (DAY)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:13, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
10:23
Pensacola (PNS)

13:42
Ronald Reagan Washington (DCA) 2
Effective 2025-05-11 through 2025-06-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:19, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
10:32
Pensacola (PNS)

13:51
Ronald Reagan Washington (DCA) 2
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 2:19, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
11:27
Philadelphia (PHL) F

12:40
Nashville (BNA)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:13, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
13:05
Charlotte (CLT)

13:59
Memphis (MEM)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
13:10
Charlotte (CLT)

14:03
Memphis (MEM)
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
14:29
Memphis (MEM)

17:28
Charlotte (CLT)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
14:33
Memphis (MEM)

17:25
Charlotte (CLT)
Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:52, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
15:43
Asheville/Hendersonville (AVL)

17:16
Ronald Reagan Washington (DCA) 2
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:33, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
15:45
Dayton (DAY)

16:10
Chicago O'Hare (ORD) 3
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:25, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
16:20
Charlotte (CLT)

17:15
Columbia (CAE)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:55, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
16:20
Charlotte (CLT)

17:16
Columbia (CAE)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 0:56, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
16:20
Charlotte (CLT)

17:20
Columbia (CAE)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:00, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
16:20
Charlotte (CLT)

17:21
Columbia (CAE)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:01, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
18:25
Columbia (CAE)

19:40
Charlotte (CLT)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:15, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
18:27
Columbia (CAE)

19:40
Charlotte (CLT)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:13, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5216
18:29
Columbia (CAE)

19:40
Charlotte (CLT)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:11, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5216
18:34
Columbia (CAE)

19:40
Charlotte (CLT)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:06, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Asheville/Hendersonville (AVL) - Ronald Reagan Washington (DCA)
  • Charlotte (CLT) - Columbia (CAE)
  • Charlotte (CLT) - Memphis (MEM)
  • Dayton (DAY) - Chicago O'Hare (ORD)
  • Pensacola (PNS) - Ronald Reagan Washington (DCA)
  • Philadelphia (PHL) - Nashville (BNA)
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