Delta Air Lines flight DL 5646: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 09:35 New York John F. Kennedy (JFK) 4 11:52 Charleston (CHS)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2025-12-24 through 2026-01-03
Daily 12:38 Charleston (CHS) 14:41 New York John F. Kennedy (JFK) 4
DL 5646 Non-stop Embraer EMB 175 (E75) 2:03 Effective 2025-12-24 through 2026-01-03
Mon-Fri,Sun 15:07 New York LaGuardia (LGA) C 17:27 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:20 Effective 2025-05-07 through 2025-06-06
Mon-Fri,Sun 15:10 New York LaGuardia (LGA) C 17:34 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:24 Effective 2025-06-08 through 2025-07-06
Sat 15:25 New York LaGuardia (LGA) C 17:49 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:24 Valid until 2025-05-03
Daily 15:55 New York LaGuardia (LGA) C 18:21 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:26 Effective 2025-07-07 through 2025-09-07
Daily 15:55 New York LaGuardia (LGA) C 18:20 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:25 Effective 2025-09-08 through 2025-12-23
Mon,Sun 15:55 New York LaGuardia (LGA) C 18:20 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:25 Effective 2026-01-04 through 2026-01-05
Daily 15:55 New York LaGuardia (LGA) C 18:26 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:31 Effective from 2026-01-06
Sat 16:00 New York LaGuardia (LGA) C 18:20 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 175 (E75) 2:20 Effective 2025-05-10 through 2025-06-07
Sat 16:00 New York LaGuardia (LGA) C 18:30 Indianapolis (IND)
DL 5646 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:30 Effective 2025-06-14 through 2025-07-05
Mon-Fri,Sun 18:07 Indianapolis (IND) 20:16 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:09 Effective 2025-05-07 through 2025-06-06
Tue-Thu,Sun 18:14 Indianapolis (IND) 20:29 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:15 Effective 2025-07-01 through 2025-07-06
Mon-Fri,Sun 18:15 Indianapolis (IND) 20:30 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:15 Effective 2025-06-08 through 2025-06-30
Fri 18:15 Indianapolis (IND) 20:30 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:15 Operates only on 2025-07-04
Tue 18:45 Pittsburgh (PIT) 20:14 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 1:29 Operates only on 2025-05-06
Mon-Fri,Sun 18:50 Pittsburgh (PIT) 20:21 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 1:31 Valid until 2025-05-02
Mon 18:50 Pittsburgh (PIT) 20:21 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 1:31 Operates only on 2025-05-05
Mon-Fri,Sun 18:50 Indianapolis (IND) 21:01 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:11 Effective 2025-09-08 through 2025-12-19
Mon,Tue,Sat,Sun 18:50 Indianapolis (IND) 21:01 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:11 Effective 2025-12-20 through 2025-12-23
Daily 18:50 Indianapolis (IND) 21:01 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 2:11 Effective from 2026-01-04
Sun 18:55 Pittsburgh (PIT) 20:26 New York LaGuardia (LGA) C
DL 5646 Non-stop Embraer EMB 175 (E75) 1:31 Operates only on 2025-05-04
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This flight number is listed as serving the following routes:


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Delta Air Lines flight DL 5646: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Delta Air Lines DL5646
09:35
New York John F. Kennedy (JFK) 4

11:52
Charleston (CHS)
Effective 2025-12-24 through 2026-01-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
12:38
Charleston (CHS)

14:41
New York John F. Kennedy (JFK) 4
Effective 2025-12-24 through 2026-01-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:07
New York LaGuardia (LGA) C

17:27
Indianapolis (IND)
Effective 2025-05-07 through 2025-06-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:20, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:10
New York LaGuardia (LGA) C

17:34
Indianapolis (IND)
Effective 2025-06-08 through 2025-07-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:24, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:25
New York LaGuardia (LGA) C

17:49
Indianapolis (IND)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:24, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:55
New York LaGuardia (LGA) C

18:21
Indianapolis (IND)
Effective 2025-07-07 through 2025-09-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:26, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:55
New York LaGuardia (LGA) C

18:20
Indianapolis (IND)
Effective 2025-09-08 through 2025-12-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:25, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:55
New York LaGuardia (LGA) C

18:20
Indianapolis (IND)
Effective 2026-01-04 through 2026-01-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:25, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
15:55
New York LaGuardia (LGA) C

18:26
Indianapolis (IND)
Effective from 2026-01-06
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:31, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
16:00
New York LaGuardia (LGA) C

18:20
Indianapolis (IND)
Effective 2025-05-10 through 2025-06-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:20, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
16:00
New York LaGuardia (LGA) C

18:30
Indianapolis (IND)
Effective 2025-06-14 through 2025-07-05
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:30, non-stop
Embraer EMB 170 / EMB 175 (E70)
Delta Air Lines DL5646
18:07
Indianapolis (IND)

20:16
New York LaGuardia (LGA) C
Effective 2025-05-07 through 2025-06-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:09, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:14
Indianapolis (IND)

20:29
New York LaGuardia (LGA) C
Effective 2025-07-01 through 2025-07-06
Mon
-
Tue
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:15
Indianapolis (IND)

20:30
New York LaGuardia (LGA) C
Effective 2025-06-08 through 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:15
Indianapolis (IND)

20:30
New York LaGuardia (LGA) C
Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:15, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:45
Pittsburgh (PIT)

20:14
New York LaGuardia (LGA) C
Operates only on 2025-05-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:29, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:50
Pittsburgh (PIT)

20:21
New York LaGuardia (LGA) C
Valid until 2025-05-02
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:31, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:50
Pittsburgh (PIT)

20:21
New York LaGuardia (LGA) C
Operates only on 2025-05-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:31, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:50
Indianapolis (IND)

21:01
New York LaGuardia (LGA) C
Effective 2025-09-08 through 2025-12-19
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:11, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:50
Indianapolis (IND)

21:01
New York LaGuardia (LGA) C
Effective 2025-12-20 through 2025-12-23
Mon
Tue
Wed
-
Thu
-
Fri
-
Sat
Sun
Duration: 2:11, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:50
Indianapolis (IND)

21:01
New York LaGuardia (LGA) C
Effective from 2026-01-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:11, non-stop
Embraer EMB 175 (E75)
Delta Air Lines DL5646
18:55
Pittsburgh (PIT)

20:26
New York LaGuardia (LGA) C
Operates only on 2025-05-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:31, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Indianapolis (IND) - New York LaGuardia (LGA)
  • New York John F. Kennedy (JFK) - Charleston (CHS)
  • Pittsburgh (PIT) - New York LaGuardia (LGA)
All Delta Air Lines flights
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- CACHE: False - LANG: en - IS_EU: False